What is a Agmatine?

Agmatine is a naturally occurring biogenic amine derived from the decarboxylation of the amino acid L-arginine. It is found primarily in the brain and nervous system, where it acts as a neurotransmitter and neuromodulator. Agmatine has attracted interest due to its neuroprotective, antidepressant, and analgesic properties, and it may support memory and learning. It modulates nitric oxide synthase (NOS), influences calcium channels and NMDA receptors, and plays roles in insulin secretion and blood pressure regulation. These actions make it a potential therapeutic candidate for conditions like depression, neuropathy, diabetes, and hypertension. As a supplement, agmatine is often taken to enhance muscle strength, mental focus, and stress resilience. While generally well-tolerated, high doses may cause side effects such as nausea, headache, or diarrhea, so consultation with a healthcare provider is advised.

※Includes information on some trading companies